68-Ga DOTATATE PET/MRI for CNS Tumors
This study is exploring whether a special type of scan, called 68-Ga DOTATATE PET/MRI, can help doctors better diagnose and manage certain brain tumors. These tumors include meningioma, esthesioneuroblastoma, hemangioblastoma, and medulloblastoma, among others, that are "somatostatin receptor positive" (meaning they have specific markers on their cells). Researchers want to see if this scan can provide more useful information than standard MRI, especially in telling the difference between a tumor growing back and changes from previous treatments. You might be able to join if you are 18 to 100 years old and have a diagnosis of meningioma with suspected recurrence, or another somatostatin receptor positive brain tumor. The study aims to evaluate the clinical benefit of this scan over a long period, up to 10 years. The current recruitment status is unclear.
- Study design
- This is an interventional study planning to enroll 200 participants. It is not specified if it is randomized or blinded.
- What's involved
- If you have meningioma and are having surgery, you would undergo a PET scan at the same time as your standard MRI before surgery. The study also involves longitudinal assessment for up to 10 years.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed with longitudinal assessment for up to 10 years to evaluate clinical benefit.
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68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Jana Ivanidze, MD/Ph.D · PRINCIPAL_INVESTIGATOR · Weill Medical College of Cornell University
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Evaluate whether Ga-68-DOTATATE PET/MRI provides additional clinical benefitLongitudinal assessment up to 10 years
Diagnostic accuracy of Ga-68-DOTATATE PET/MRI will be compared to MRI alone. Correlative analyses will be performed including logistic regression/ Spearman correlation for continuous variables, and Mann-Whitney U tests for not normally distributed subgroups for variables allowing for dichotomization.