This study is testing a small device called a "nanosensor" to see if it can accurately measure oxygen levels in muscle. Oxygen levels are a way to check how well mitochondria (the powerhouses of your cells) are working. The nanosensor is 1.8 mm wide, 6 mm long, and 0.3 mm deep. It has not been tested in people before or approved by the FDA. Researchers hope this nanosensor can help tell the difference between people with mitochondrial myopathies (muscle diseases caused by mitochondrial problems) and healthy individuals. This could lead to better ways to measure how well new treatments for mitochondrial diseases are working. The study plans to enroll 24 participants, including people aged 18 to 65 with mitochondrial myopathy and healthy volunteers.

Study design

This interventional study will involve 24 participants, including individuals with mitochondrial myopathy and healthy volunteers. It is an investigational device clinical trial.

What's involved

You would have the nanosensor placed in your forearm under local anesthesia. You would then perform handgrip exercises, and these measurements would be repeated 7 to 30 days later.

Compensation

Not stated in the trial record.

Follow-up

Nanosensor-muscle oxygen levels will be measured at 60 minutes for data collection at each of 2 study visits, up to 6 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.