Understanding Neutrophils in Pediatric Sepsis
This observational study aims to understand how neutrophils (a type of white blood cell that fights infection) behave in children with sepsis. Sepsis is a severe infection that can harm organs. While neutrophils are important for fighting germs, they can also cause organ damage in sepsis. Researchers want to learn about the different types of neutrophils present in the blood of children with sepsis to help develop better treatments. The study is looking for 72 children, aged 1 month to 17 years, who have sepsis or are scheduled for elective surgery (control group). The main goal is to study neutrophil populations for up to one month.
- Study design
- This is an observational study planning to enroll 72 participants. It is not a treatment study but rather focuses on understanding a condition.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants' neutrophil populations will be measured for up to one month.
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Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Koichi Yuki, MD · PRINCIPAL_INVESTIGATOR · Boston Children's Hospital
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- neutrophil populationsup to 1 month
compare gene expression in neutrophils between sepsis patients and non-sepsis patients in pediatric population to report unregulated and down regulated genes