Shingrix in Kidney Transplant Recipients
This study is looking at how well the shingles vaccine, Shingrix, works and how safe it is for adults with kidney failure who are waiting for a kidney transplant. It also wants to see if an extra dose of Shingrix after a transplant can improve protection. Researchers will measure your body's immune response to the vaccine at different times over 12 months after vaccination. You might be able to join if you are 18 to 70 years old, have chronic kidney failure, and are on a waiting list for a kidney transplant. The study aims to enroll 132 participants, but its current status is unclear.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 132 participants.
- What's involved
- Participants will receive the standard Shingrix vaccine. The study will measure your immune response at 12 months after vaccination.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your immune response will be measured at 12 months after vaccination.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Shingrix in Renal Transplant Recipients
At a glance
Conditions
Where it's being run
4 sites across 4 statesStudy leadership
- Myron J Levin, MD · PRINCIPAL_INVESTIGATOR · University of Colorado Anschutz School of Medicine
Who to contact
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What this trial measures
- gE-Specific IL-2 T Cell Response at 12 Months After Randomization12 months after vaccination
1\. gE-Specific IL-2 T Cell Response at 12 Months After Randomization Description: Cellular immune response measured by gE-specific IL-2-producing spot-forming cells (SFC) per 10⁶ peripheral blood mononuclear cells (PBMC) using FluoroSpot assay in renal transplant recipients. Comparison between participants who receive a third dose of Shingrix post-transplant and those who do not receive a third dose. Time frame: 12 months after vaccination (post-transplant)