Human Visual and Vestibular Motion Perception Study

This study is looking at how people perceive motion using their vision and their vestibular system (inner ear balance system). Researchers want to understand how aging and certain conditions like vestibular disease affect this perception. You would participate in activities called "heading direction adaptation," where you'll experience visual environments that include rotation and situations where what you see and what your body feels are intentionally different. The main goal is to see how your perception of heading changes from the beginning of the study to one week later. This study is open to healthy individuals and those with specific types of vestibular disease, aged 18 to 80 years old.

Study design
This is an interventional study with a planned enrollment of 300 participants. It is not specified if it is randomized or blinded.
What's involved
You would participate in behavioral interventions involving exposure to visual environments. The primary endpoint is measured at baseline and at one week.
Compensation
Not stated in the trial record.
Follow-up
Your heading perception will be measured at baseline and again at one week.

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NCT04142697

Human Visual and Vestibular Motion Perception Study

Recruiting
NAAges 18–80InterventionalBasic science
University of Rochester
~300 participants
Updated 2026-01-12 on ClinicalTrials.gov
What's tested:Heading direction adaptation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Mean Heading perception
Measured over Baseline to 1 week
Vestibular Disease
1 sites across 1 states
New York1

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Eligibility criteria

Inclusion

general good health
general good health
specific unilateral or bilateral vestibular loss

Exclusion

subjects who are institutionalized or otherwise not self-sufficient.
enduring sequelae due to diseases of the nervous system, eyes, ears, head and neck, and limbs, except for changes commensurate with normal aging (e.g. presbyacusic hearing loss, mild cataract, etc.).
abnormal cognitive function, which if in question can be determined as a score of \<27 on the Mini-Mental State test.
corrected visual acuity worse than 20/20 up to age 65, worse than 20/40 if \>65
abnormal binocular stereo-acuity or visual fields.
any defects in cranial nerve, oculomotor, cerebellar/coordination, and somatosensory functions.
any abnormal oculomotor and vestibular function (caloric tests)
Inability to perform the study tasks due to sensory, motor, or postural limitations
  • Change in Mean Heading perceptionBaseline to 1 week

    Heading perception will be measured using two alternative forced choice and magnitude estimation procedures and reported in degrees. It is measured in degrees of azimuth with positive to the right and negative to the left of straight ahead (defined as 0 degrees).