Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
This study is testing if combining transcranial direct current stimulation (tDCS) with Verb Network Strengthening Treatment (VNeST) can improve language abilities in people with chronic aphasia (difficulty with language after a stroke). tDCS involves placing two damp sponges on your scalp and passing a weak electrical current between them to change brain activity. One sponge is placed near language areas above your left ear, and the other on your forehead above your right eye. You would receive tDCS during the first 20 minutes of your twice-weekly VNeST therapy sessions for 8 weeks. The study aims to see if this combination helps you produce more correct information in your speech. They plan to enroll 30 participants, including those with post-stroke aphasia and healthy volunteers.
- Study design
- This is an interventional study that plans to enroll 30 participants. It compares active tDCS with sham (inactive) tDCS during speech therapy, and the therapist will not know which type of stimulation you are receiving.
- What's involved
- You would complete four behavioral assessments and four brain scans (MRI). Two assessments and scans happen before treatment, one immediately after, and one 8 weeks later. Therapy sessions are 60 minutes, twice weekly for 8 weeks, and you cannot receive other speech therapy during the study (about 20 weeks).
- Compensation
- Not stated in the trial record.
- Follow-up
- Your language abilities will be assessed immediately after treatment and again 8 weeks after treatment.
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Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
At a glance
Conditions
NCT04142866
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
City University of New York
New York, New Yorkstudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- E. Susan Duncan, PhD, CCC-SLP · PRINCIPAL_INVESTIGATOR · City University of New York
Who to contact
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Inclusion
Exclusion
What this trial measures
- Production of Correct Information Units (CIUs) on Discourse TasksCollected twice at baseline, immediately (<1 week) post-treatment, and at 8 week follow-up
Change in CIU production over treatment interval. Words are counted as CIUs if they are novel, intelligible, informative, and appropriate in context (Nicholas \& Brookshire, 1993).