This study is looking at a new way to help women with Polycystic Ovary Syndrome (PCOS) get pregnant using in vitro maturation (IVM). IVM involves collecting immature eggs and letting them mature in the lab before fertilization. This study uses oral medications like letrozole and very low doses of FSH (follicle-stimulating hormone) to prepare the ovaries, and a special needle (Steiner-Tan) for egg retrieval. After fertilization, embryos are frozen and transferred in a later cycle. We want to see how many patients become pregnant after 12 weeks and how many have an ongoing pregnancy after 10 months. You may be able to join if you are a woman between 18 and 38 years old, have a specific pattern of follicles in your ovaries (PCO pattern), and an AMH (Anti-Müllerian Hormone) level above 3.5. We cannot tell you if the study is currently enrolling.

Study design

This is an interventional study with a planned enrollment of 300 participants. All participants will receive the IVM treatment.

What's involved

You will take oral contraceptives, then oral letrozole and low-dose FSH. You will have an HCG injection, followed by egg retrieval approximately 38 hours later. Embryos will be frozen and transferred in a separate cycle.

Compensation

Not stated in the trial record.

Follow-up

Your pregnancy status will be checked at 12 weeks after embryo transfer and again at 10 months after embryo transfer.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.