Duke APOL1 Research Biorepository for Kidney Disease

This study is collecting biological samples (blood and urine) and medical information from adults to better understand kidney disease, especially in people of African ancestry. Researchers are interested in the ApoL1 gene, which is linked to kidney disease in individuals of recent African descent. The goal is to create a collection of samples that can be used to study why some people with ApoL1 mutations develop kidney failure and others don't. This research could help scientists understand the causes of kidney disease and potentially lead to new ways to prevent or treat it. The study aims to enroll 200 participants.

Study design
This is an observational study, meaning researchers will collect information and samples without giving any specific treatment. It plans to enroll 200 participants.
What's involved
You would provide biological samples (whole blood and urine) and relevant medical information. The duration of your participation is not specified.
Compensation
Not stated in the trial record.
Follow-up
The biorepository will be measured at 5 years, but individual participant follow-up is not specified.

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NCT04160507

Duke APOL1 Research Biorepository

Recruiting
Not specifiedAges 18+Observational
Duke University
~200 participants
Updated 2026-08-27 on ClinicalTrials.gov
What's tested:Biorepository

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Biorepository
Measured over 5 years
End Stage Kidney Disease
1 sites across 1 states
North Carolina1

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Eligibility criteria

Inclusion

Majority of subjects recruited for this study will be self-identified African Americans, Afro-Caribbean and other black individuals. Study subjects will include individuals at various stages of kidney disease and those without any clinical evidence of kidney disease.
Healthy black adults, age 50 and older with no known history of kidney disease will be recruited as controls

Exclusion

Black adult cases with diabetic nephropathy
Healthy controls with kidney disease
  • Biorepository5 years

    Number of biological samples collected and stored (whole blood and urine).