This study is looking at whether magnesium sulfate, a common medication that contains magnesium, can help manage pain in critically ill trauma patients. Magnesium is a natural mineral important for your body and brain, and magnesium sulfate has been used for pain control in surgery. Researchers want to see if giving magnesium sulfate through an IV (intravenous) can reduce the amount of opioid pain medication needed by patients with serious injuries. You might be able to join if you are an adult trauma patient admitted to an intensive care unit (ICU) and are between 18 and 99 years old. The study will measure how much opioid medication is needed over 24 hours to see if magnesium sulfate is effective. The current status of this study is unclear.

Study design

This is a randomized controlled study, meaning participants will be randomly assigned to receive either magnesium sulfate or a placebo (normal saline). It is also double-blind, so neither you nor your doctors will know which treatment you are receiving. The study plans to enroll 156 participants.

What's involved

You would receive either magnesium sulfate or normal saline through an IV, starting with a bolus (a single, larger dose) followed by a continuous infusion for 24 hours.

Compensation

Not stated in the trial record.

Follow-up

Your opioid requirements will be measured for 24 hours during the study drug infusion.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.