Glucose Variability and Cognition in Prediabetes
This study is looking at how changes in your blood sugar levels (glucose variability) might be connected to your thinking abilities (cognitive function) and how well you perform daily activities (functional status) if you have prediabetes. Researchers want to see if even before diabetes develops, these blood sugar changes affect your brain and daily life. You would wear a Continuous Glucose Monitoring System (CGMS), a small device that measures your glucose levels for 10 days. The study will measure your executive functioning, memory, and language skills after this 10-day period. This study is for people aged 50 and older with prediabetes, who have at least an 8th-grade education. People with diagnosed type 1 or type 2 diabetes, or those taking diabetes medications, cannot participate. The current status of this study is unclear.
- Study design
- This is an observational study, meaning participants will be monitored without receiving a specific treatment. It plans to enroll 30 participants.
- What's involved
- You would wear a Continuous Glucose Monitoring System (CGMS) for 10 days at home. You would also have two study visits for assessments of your functional status, thinking abilities, and to gather information about your health and mood.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your cognitive function and functional status will be measured at Day 10.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Glucose Variability and Cognition in Prediabetes
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Tasneem Khambaty, PhD · PRINCIPAL_INVESTIGATOR · University of Maryland, Baltimore County
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Aggregate Executive Functioning ScoreDay 10
Scores on the following standard neurocognitive tests will be z-transformed based on their respective means and standard deviations and combined into one aggregate total score such that higher values mean better executive functioning: Trails Making A and B, The Stroop-Color Word Test, Digit Span subscale of the Wechsler Adult Intelligence Scale - Revised (WAIS-IV), Digit Symbol Substitution Test (DSST)
- Aggregate Memory ScoreDay 10
Scores on the following standard neurocognitive tests will be z-transformed based on their respective means and standard deviations and combined into one aggregate total score such that higher values mean better memory ability: California Verbal Learning Test, Benton Visual Retention Test
- Aggregate Language ScoreDay 10
Scores on the following standard neurocognitive tests will be z-transformed based on their respective means and standard deviations and combined into one aggregate total score such that higher values mean better language abilities: Boston Naming Test, Controlled Oral Word Association Test (COWA)