Oral Nutritional Optimization in Total Joint Arthroplasty

This study is looking at how nutritional support might help patients having total hip or knee replacement surgery for osteoarthritis. Researchers want to see if giving patients a nutritional drink called Ensure Max Protein Shake before and after surgery can improve their nutritional status. You might be able to join if you are 55 to 95 years old, are scheduled for a total hip or knee replacement, and have certain low levels of proteins in your blood (albumin, pre-albumin, or transferrin), which can indicate malnutrition. The study will measure these protein levels to see if the nutritional drink makes a difference. The study is currently unclear on its recruitment status and plans to enroll 72 participants.

Study design
This is an interventional study planning to enroll 72 participants. The study aims to investigate the effect of oral nutritional supplementation.
What's involved
You would have blood tests to measure your albumin, pre-albumin, and/or transferrin levels at two weeks before surgery, on the day of surgery, and four weeks after surgery.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for at least four weeks after surgery, based on the primary endpoint measurements.

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NCT04210284

Oral Nutritional Optimization in Total Joint Arthroplasty

Recruiting
NAAges 55+InterventionalTreatment
NYU Langone Health
~72 participants
Updated 2025-09-11 on ClinicalTrials.gov
What's tested:Ensure

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Changes in the patients' albumin, pre-albumin, and/or transferrin levels
Measured over Visit 2 (2 wks pre) Visit 3 (surgery day) Visit 5 (4 weeks post)
Osteoarthritis
2 sites across 2 states
New York1
Pennsylvania1
  • Ran Schwarzkopf · PRINCIPAL_INVESTIGATOR · NYU Langone

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  • Changes in the patients' albumin, pre-albumin, and/or transferrin levelsVisit 2 (2 wks pre) Visit 3 (surgery day) Visit 5 (4 weeks post)

    Biological specimen collection and laboratory evaluations- all included patients' hematologic markers of malnutrition (albumin, pre-albumin, and transferrin) will be recorded at 2 weeks prior to surgery, the day of surgery, and 6 weeks. These blood tests can all be performed from one sample of blood at each visit. The results will then be accessed via the EMR