Observational Study on Type 2 Immunity and NAFLD in Obesity
This observational study aims to understand how inflammation in fat tissue (adipose tissue) is connected to fat buildup around the liver (NAFLD) and insulin resistance in people with obesity. Researchers will evaluate liver scarring (fibrosis) using elastography before gastric bypass surgery. You may be able to join if you are between 30 and 70 years old, have a BMI over 40 kg/m2, are having gastric bypass surgery, and have confirmed liver fibrosis. The study is looking for 60 participants. The current recruitment status is unclear.
- Study design
- This is an observational study planning to enroll 60 participants. It is not a treatment study, but rather looks at existing conditions.
- What's involved
- Participants will have their liver fibrosis and adipose tissue inflammation measured at the beginning of the study.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Elena Anna O De Filippis · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Liver fibrosisBaseline
evaluate the liver fibrosis by elastography before surgical intervention
- Adipose tissue inflammationBaseline
Evaluate markers of adipose tissue inflammation by mRNA levels