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Observational Study of Early Liver Transplants for Severe Alcoholic Hepatitis

This observational study is looking at patients with severe alcoholic hepatitis (SAH) who receive an early liver transplant. Researchers want to understand how well patients do after this type of transplant, specifically how many are still alive one year later. They also want to gather opinions from healthcare providers and the public to help create guidelines for these transplants. You might be able to join if you have severe alcoholic hepatitis, are at least 18 years old, and are listed for a liver transplant at Johns Hopkins Hospital, even if you haven't been sober for six months.

Study design
This is an observational study aiming to enroll 300 participants. It is not a randomized trial and does not involve a specific phase of drug development.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed to measure survival within one year after their transplant.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04234139

Cohort/Ethics Study of Patients With Severe Alcoholic Hepatitis Undergoing Early Liver Transplantation

Enrolling by Invitation
Not specifiedAges 18+Observational
Johns Hopkins University
~300 participants
Updated 2025-12-16 on ClinicalTrials.gov
What's tested:liver transplant

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of participants who survived within 1 year post-transplant
Measured over 1 years

Conditions

Liver Diseases, Alcoholic
Alcohol-Related Disorders
Transplant; Failure, Liver
Transplant; Complication, Rejection
Liver Diseases
Hepatitis, Alcoholic
Alcohol-Induced Disorders

Explore related trials

Alcoholic Liver DiseaseSevere Alcoholic Hepatitis

Where it's being run

1 sites across 1 states
Maryland1

Study leadership

  • Andrew M Cameron, MD, PhD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patients with Severe Alcoholic Hepatitis (SAH) listed for liver transplantation at Johns Hopkins Hospital (JHH), have not been sober for at least 6 months at time of waitlisting, and are at least 18 years old.
Patients 18 years or older undergoing liver transplantation at JHH for alcoholic liver disease and were sober for at least 6 months prior to transplantation.

Exclusion

Non-SAH patients listed for liver transplantation at JHH and patients who have been sober for at least 6 months at the time of waitlisting.

What this trial measures

  • Number of participants who survived within 1 year post-transplant1 years

    Post-transplant survival within one year of the surgical procedure.