Theophylline for Pseudohypoparathyroidism

This study is testing the long-term effects of theophylline ER (a drug taken by mouth) for people with pseudohypoparathyroidism (PHP), a genetic condition affecting growth and hormones. Researchers want to see if theophylline ER can help with weight, how the body handles sugar, and hormone resistance. You can join if you are between 2 and 99 years old and have already finished a previous study on theophylline for PHP. The main goal is to check for any side effects over 24 months. This study is currently unclear about its recruitment status.

Study design
This is a single-center, open-label extension study for 34 participants who completed a previous randomized trial. It is a Phase 2 study.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for adverse events for 24 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04240821

Theophylline for Treatment of Pseudohypoparathyroidism

Enrolling by Invitation
PHASE2Ages 2–99InterventionalTreatment
Jaclyn Tamaroff
~34 participants
Updated 2026-04-28 on ClinicalTrials.gov
What's tested:Theophylline ER

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Adverse Events
Measured over 24 months
Pseudohypoparathyroidism
Pseudohypoparathyroidism Type 1a
Albright Hereditary Osteodystrophy
1 sites across 1 states
Tennessee1
  • Jaclyn Tamaroff, MD · PRINCIPAL_INVESTIGATOR · Vanderbilt University Medical Center

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

1\. Successful completion of the randomized clinical trial "Phase 2 Study of Theophylline Treatment of Pseudohypoparathyroidism IND 133103 (11/1/2016)".
  • Adverse Events24 months

    Treatment-emergent adverse events will be compared before and during treatment