Understanding Brain Blood Flow with Respiratory Challenges
This study aims to understand how blood flow and metabolism (how your body uses energy) differ in the brain between healthy individuals and those with brain vascular (blood vessel) conditions. Researchers will use magnetic resonance imaging (MRI) to examine brain blood flow while you breathe in different air mixtures, including air with added carbon dioxide. The main goal is to measure how much oxygen your brain uses during the MRI scan, which lasts about 75 minutes. You may be eligible if you are a healthy adult or an adult with a brain vascular condition, are at least 18 years old, can have an MRI without sedation, are not on stimulant medications, and have no history of psychiatric treatment.
- Study design
- This interventional study plans to enroll 48 participants. It is not specified if participants will be randomly assigned to groups or if the study is blinded.
- What's involved
- You would participate in an MRI scan where you will inhale carbon dioxide. The MRI scan and oxygen metabolism measurement will take about 75 minutes.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary measurement of cerebral oxygen metabolism occurs from the beginning to the completion of the 75-minute MRI scan.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The Effect of Respiratory Challenge on the BOLD Signal
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Exclusion
What this trial measures
- Cerebral Oxygen MetabolismFrom the beginning of the MRI scan to the completion of the MRI scan -- 75 minutes.