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Understanding How Your Brain Processes Audiovisual Speech

This study aims to understand how your brain uses both sounds (auditory) and sights (visual) to understand speech. Researchers will present audiovisual speech and measure your brain activity using electrodes (intracranial encephalography) during a neurosurgery you are already undergoing for a brain disorder. This study is looking for 100 participants between 21 and 65 years old who have normal vision and hearing (with correction if needed). The main goal is to measure brain activity during this procedure to learn more about speech perception.

Study design
This is an interventional study planning to enroll 100 participants. It is not specified if it is randomized or blinded.
What's involved
You would have your brain activity measured using electrodes while audiovisual speech is presented during a neurosurgery you are already undergoing.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04290130

Dynamic Neural Mechanisms of Audiovisual Speech Perception

Enrolling by Invitation
NAAges 21–65InterventionalBasic science
University of Pennsylvania
~100 participants
Updated 2025-09-10 on ClinicalTrials.gov
What's tested:Measurement of brain activity using electrodes.

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Measurement of neural activity
Measured over During the procedure.

Conditions

Speech Perception

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Speech Perception

Where it's being run

1 sites across 1 states
Pennsylvania1

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

must be undergoing neurosurgery for the treatment of a brain disorder

Exclusion

must have corrected-to-normal vision and hearing

What this trial measures

  • Measurement of neural activityDuring the procedure.

    The name of the measurement is the broadband high-frequency activity (BHA) in the brain in response to audiovisual speech. The unit of measure is % increase in power from pre-stimulus baseline. The name of the measurement tool is intracranial EEG, recordings of the raw voltage signal from each electrode implanted in the brain. The voltage-by-time signal will be converted to spectral space using a wavelet transform, and the magnitude of the power between 70 and 150 Hz inclusive in a time window between 0 ms and 500 ms after stimulus onset will be calculated.