Observational Study: Stool Bank for Cancer Patients on Immunotherapy

This study is collecting stool samples from people with cancer, specifically non-small cell lung carcinoma and colorectal carcinoma, who are receiving immunotherapy like pembrolizumab. Researchers want to understand how the bacteria in your gut (gut microbiota) affect how well these cancer treatments work. By studying these samples, they hope to identify specific bacteria that help make treatments more effective. This information could lead to new ways to improve cancer care. The study aims to enroll 100 participants and will look at treatment response after 6-12 months.

Study design
This is an observational study, meaning you won't receive a new treatment. It involves 100 participants across two locations.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Researchers will look at your checkpoint inhibitor response between 6 and 12 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04291755

Development and Analysis of a Stool Bank for Cancer Patients

Recruiting
Not specifiedAges 18+Observational
Persephone Biosciences
~100 participants
Updated 2024-04-05 on ClinicalTrials.gov
What's tested:Pembrolizumab Injection

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Checkpoint inhibitor response
Measured over 6-12 months
Carcinoma, Non-Small-Cell Lung
Carcinoma, Colorectal
2 sites across 2 states
California1
Florida1

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Eligibility criteria

Inclusion

Men or women who are ≥ 18 years old who are undergoing any type of cancer immunotherapy
Subjects who are able to provide written informed consent

Exclusion

Subjects with HIV, Hepatitis B, or Hepatitis C
Subjects without the mental capacity to complete either a written or online questionnaire, alone or with assistance, or make sound decisions
Women who are pregnant or who plan on becoming pregnant
Women who are nursing
  • Checkpoint inhibitor response6-12 months

    Response of the tumor to treatment, as evaluated by the iRECIST criteria