Observational Study of Visual Function in Amblyopia and Strabismus

This study is looking at how different visual abilities are affected by amblyopia (often called "lazy eye") and strabismus (crossed eyes), and how these abilities change with treatment. Researchers will measure various visual functions, like how well you see details or colors, in people with these conditions. The treatments being observed include patching therapy, glasses, and strabismus surgery. The goal is to understand if current treatments fully correct these visual problems. You may be able to join if you are between 6 months and 90 years old and have a history of amblyopia or risk factors for it. The study is currently unclear on its recruitment status and plans to enroll 150 participants.

Study design
This is an observational study, meaning researchers will watch how treatments like patching, glasses, and surgery affect visual functions over time. It is not a clinical trial testing a new treatment.
What's involved
You would have various visual functions measured before, during, and after treatment for amblyopia or strabismus. These measurements may include eye movements, contrast sensitivity, and visual acuity.
Compensation
Not stated in the trial record.
Follow-up
Visual functions will be measured for up to 3 years, depending on the duration of your treatment.

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NCT04310241

Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy

Recruiting
Not specifiedAges 6–90Observational
The Cleveland Clinic
~150 participants
Updated 2026-03-04 on ClinicalTrials.gov
What's tested:Patching therapy, Glasses

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Visual Functions
Measured over 0-3 years depending on duration of treatment
+6 more outcomes measured
Amblyopia
Strabismus
1 sites across 1 states
Ohio1
  • Fatema Ghasia, MD · PRINCIPAL_INVESTIGATOR · The Cleveland Clinic

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Eligibility criteria

Inclusion

History of amblyopia or presence of amblyogenic risk factors.

Exclusion

History of neurologic disorders
  • Visual Functions0-3 years depending on duration of treatment

    contrast sensitivity

  • Visual Functions0-3 years depending on duration of treatment

    visual acuity

  • Visual functions0-3 years depending on duration of treatment

    vernier acuity

  • Visual functions0-3 years depending on duration of treatment

    grating acuity

  • Visual functions0-3 years depending on duration of treatment

    binocular functions- stereopsis, inter-ocular functions

  • Visual functions0-3 years depending on duration of treatment

    eye movement measurements

  • Visual functions0-3 years depending on duration of treatment

    reading- reading speeds, eye movement measurements