Back to search results

Combining MyoCI and Memory Reactivation for Stroke Recovery

This study is looking at whether combining MyoCI (myoelectric computer interface) training with Targeted Memory Reactivation (TMR) can help improve arm movement in people who have had a stroke. TMR involves playing audio cues quietly during sleep to help strengthen memories. The study wants to see if this training, along with sleep support, can lead to better arm function. You may be able to join if you are 21 or older, have arm weakness from a stroke at least 6 months ago, and have some voluntary shoulder and elbow movement. The main way they will measure success is by looking at changes in your arm function using the Wolf Motor Function Test (WMFT) after 6 weeks. The current recruitment status is unclear.

Study design
This is an interventional study with a planned enrollment of 70 participants. The phase of the study is not specified.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Arm motor function will be measured at 6 weeks after the start of the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04312269

Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke

Recruiting
NAAges 21+InterventionalTreatment
Northwestern University
~70 participants
Updated 2026-05-27 on ClinicalTrials.gov
What's tested:Targeted Memory Reactivation (TMR)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Wolf Motor Function Test (WMFT)
Measured over change from baseline at 6 weeks

Conditions

Stroke

Explore related trials

Stroke

NCT04312269

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Northwestern University

    Chicago, Illinoisno site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Marc W Slutzky, MD/PhD · PRINCIPAL_INVESTIGATOR · Northwestern University

Who to contact

Marc W Slutzky, MD/PhD
[email protected]
312-503-4653
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Age at enrollment is 21 or older
Hemiparesis from first ever stroke affecting arm movement at least 6 months prior to screening
Severe to moderate motor impairment (FMA-UE of 7-40)
At least some voluntary shoulder and elbow muscle activation

Exclusion

Inability to follow instructions of the MyoCI task
Visual impairment (such as hemianopia) preventing full view of screen
Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest)
Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study
Inability to understand or follow commands in English due to aphasia or other reason
Diffuse or multifocal infarcts in both hemispheres
Substantial arm pain preventing participation for 90 minutes a day
Spasticity treatment (pharmacological or Botox) within last 3 months
Ferromagnetic implants that are MRI incompatible

What this trial measures

  • Wolf Motor Function Test (WMFT)change from baseline at 6 weeks

    The WMFT evaluates upper extremity function on a continuous scale. It measures the time it takes to perform 15 different tasks, with a time limit of 120 s per task.