Study of Circulating Monocytes in Patients With Ischemic Vascular Disease
This observational study is looking at how certain white blood cells, called monocytes, and other substances in your blood react after a heart attack (myocardial infarction) or an ischemic stroke (a stroke caused by a blood clot). Researchers are particularly interested in a type of monocyte with a surface marker called "P2X4." They want to understand how these cells respond to injury in heart and brain tissue and if they produce chemicals that help with healing. The study aims to measure the levels of these monocytes and other related markers in patients at different times after a heart attack or stroke, comparing them to people with stable heart disease and healthy individuals. The main goal is to see if these measurements can help predict future heart attacks, strokes, or death over three years. This study is currently unclear on its recruitment status and plans to enroll 300 participants.
- Study design
- This is an observational study with no specified phase, involving 300 planned participants.
- What's involved
- You would provide three blood samples at different times: within 48 hours of hospital admission, 2-14 days later, and 30-120 days after a heart attack or stroke.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for three years to track hospitalizations for heart attack, stroke, or death.
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Study of Circulating Monocytes in Patients With Ischemic Vascular Disease
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Bruce Liang, MD · PRINCIPAL_INVESTIGATOR · UConn Health
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Hospitalization for Myocardial Infarction, Stroke, or death3 years
myocardial infarction, stroke or death