Spinal Cord Stimulation for Obesity and Type 2 Diabetes
This study is exploring if spinal cord stimulation (SCS), a treatment often used for pain, can help with weight loss and Type 2 diabetes. Researchers will place a second research electrode in your upper back during your planned SCS implant procedure. They will then measure changes in your body's metabolism (how your body uses energy) after one week. This study is for people aged 21-70 who have ongoing leg and back pain, are already planning to get SCS for pain, and have a body mass index (BMI) between 25 and 45. The goal is to see if SCS can activate brown adipose tissue (BAT), a type of fat that burns calories, which could lead to new ways to treat obesity and Type 2 diabetes. The current recruitment status is unclear.
- Study design
- This is an interventional study with a planned enrollment of 10 participants. It is not specified if it is randomized or blinded.
- What's involved
- You would have a second research electrode placed during your planned spinal cord stimulator (SCS) implant procedure. Your metabolism will be measured after one week using a PET scan.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for one week to measure the primary endpoint.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Brown Adipose Tissue Activation by Spinal Cord Stimulation
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Kim Burchiel, MD · PRINCIPAL_INVESTIGATOR · Oregon Health and Science University
Who to contact
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What this trial measures
- SUVmax1 week
Maximum standardized uptake value (SUVmax) of bilateral cervical and supraclavicular regions during SCS activation, in comparison to baseline imaging