Back to search results

The Allergen Reduction and Child Health Study (ARCHS) for Childhood Asthma

The ARCHS study is looking for children aged 5 to 17 in the Greater New Orleans area who have uncontrolled asthma and are exposed to cockroaches. This 12-month study compares two approaches to reduce cockroach exposure: a "tailored approach" that includes education, cockroach baiting, mattress covers, a HEPA vacuum, and an air purifier, versus just "cockroach bait." The goal is to see if reducing cockroach exposure can improve asthma symptoms, reduce hospital visits, and improve asthma control. To join, children must have uncontrolled persistent asthma, meaning they've had recent hospitalizations or emergency room visits for asthma, and are either on controller medication or have frequent symptoms. The study's status is currently unclear.

Study design
This is a 12-month randomized controlled trial with two groups, aiming to enroll 290 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months to measure asthma symptoms, hospitalizations, and asthma control.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04331353

The Allergen Reduction and Child Health Study (ARCHS)

Recruiting
NAAges 5–17InterventionalTreatment
Tulane University
~290 participants
Updated 2025-09-09 on ClinicalTrials.gov
What's tested:Comparator 1 (tailored approach)Comparator 2 (insecticidal bait)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Maximum number of symptom days in the previous two weeks
Measured over 12 Months
+2 more outcomes measured

Conditions

Asthma in Children

Explore related trials

Asthma

Where it's being run

1 sites across 1 states
Louisiana1

Study leadership

  • Felicia Rabito, PhD · PRINCIPAL_INVESTIGATOR · Tulane University School of Public Health and Tropical Medicine

Who to contact

Derek Werthmann, PhD
[email protected]
5049882386
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Age 5 - 17 years; with uncontrolled persistent asthma defined as the child experiencing at least one of the following: one overnight hospitalization for asthma within the past six months OR two unscheduled clinic or emergency department visits for asthma within the last 12 months; and either on a long term controller medication for asthma, or have asthma symptoms 3 or more days per week over the past 2 weeks or nighttime asthma symptoms at least 3 times in the past month exposure to cockroach - defined as trapping at least one cockroach in a 3 day period OR visual evidence of cockroaches by field staff; and the child must sleep in the target home at least 4 nights per week on average. Caregiver ability to speak English or Spanish.

Exclusion

Other serious medical or chronic illnesses including chronic respiratory infections that require daily medication, cardiovascular disease that requires daily medication, excluding hypertension, taking a beta-blocker, a current active smoker, currently receiving immunotherapy or plans to move within the 12 month follow-up.

What this trial measures

  • Maximum number of symptom days in the previous two weeks12 Months

    The number of days with asthma symptoms (chest tightness, cough, wheeze, disrupted sleep, limitations on physical activities) in the previous two weeks.

  • Number of participants with an asthma related hospitalization, unscheduled clinic or emergency room visit for asthma in the previous month12 Months

    Hospitalization or emergency room visit for asthma or unscheduled doctor visit for asthma in the previous month.

  • Level of Asthma control12 Months

    The level of asthma control assessed using the Asthma Control Test. The scores range from 5 to 25 with higher scores reflecting greater asthma control.