The Alaska Oculocardiac Reflex Study

This study is observing how your heart rate changes during strabismus surgery. Strabismus is when your eyes don't line up correctly, sometimes called "crossed eyes." Researchers will use an electrocardiograph (a device that records your heart's electrical activity) to monitor your heart rate when doctors gently pull on your eye muscles during surgery. This is to understand the oculocardiac reflex, which is when eye manipulation affects your heart rate. The study is looking for 4000 participants aged 1 month to 100 years who are having eye manipulation or strabismus surgery. You cannot join if you have anophthalmia (absence of one or both eyes). The main goal is to measure the percentage change in heart rate caused by this reflex, specifically 30 seconds after the eye muscle is pulled.

Study design
This is an observational study involving 4000 participants. It is not specified if it is randomized or blinded.
What's involved
If you participate, your vital signs and anesthetic variables, including heart rate, will be monitored before, during, and after your eye surgery.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome is measured at 30 seconds after the oculocardiac reflex is elicited.

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NCT04353960

The Alaska Oculocardiac Reflex Study

Recruiting
Not specifiedAges 1+Observational
Alaska Blind Child Discovery
~4,000 participants
Updated 2024-07-31 on ClinicalTrials.gov
What's tested:electrocardiograph

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percent heart rate resulting from oculocardiac reflex
Measured over 30 seconds
Bradycardia
Strabismus
1 sites across 1 states
Alaska1
  • Robert W Arnold, MD · PRINCIPAL_INVESTIGATOR · Alaska Blind Child Discovery

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patient scheduled for ocular manipulation and tension on extra ocular muscles and strabismus surgery

Exclusion

anophthalmia
  • Percent heart rate resulting from oculocardiac reflex30 seconds

    Continuous variable of percent change in heart rate from stable pre-heart rate to greatest change heart rate during strabismus surgery