This pilot study is looking at whether deep brain stimulation (DBS) of the nucleus accumbens (NAc) can help people with opioid use disorder (OUD) who haven't found success with other treatments. DBS involves placing a small device in the brain to send electrical signals. Researchers want to see if this treatment is safe and if it can help reduce opioid use and cravings. The study plans to enroll 3 individuals, aged 22 to 65, who have had OUD for at least 5 years and have tried at least two other treatments without lasting success. The main goals are to see how much opioid use changes at 6 months and 1 year after surgery. The current recruitment status for this study is unclear.

Study design

This is a pilot study involving 3 participants with treatment-resistant opioid use disorder. It is an interventional study, meaning participants will receive a specific treatment.

What's involved

Participants will undergo surgery to implant DBS devices and will have an overnight hospital stay. They will have follow-up visits for device testing and programming, and will continue standard addiction treatment.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed to measure opioid use/abstinence at 6 months and 1 year post-surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.