ACDF Using Structural Allograft vs. Tritanium C for Degenerative Disc Disease

This study is looking at the success of two different surgical approaches for treating degenerative disc disease (DDD) in your neck. It compares the Tritanium C anterior cervical cage with a traditional structural allograft (bone graft) procedure. Researchers want to see how well each method helps the bones in your neck fuse together after surgery. You might be able to join if you are between 18 and 80 years old, have DDD at one or two levels in your neck, and have already tried at least six weeks of other treatments like injections or physical therapy. The main goal is to measure how long it takes for the bones to fuse at 3, 6, and 12 months after surgery. The study status is unclear.

Study design
This is an observational study that will collect data from 60 participants. It will compare new patients receiving Tritanium C with a group of past patients who received structural allograft.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed to assess fusion at 3, 6, and 12 months after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04388332

ACDF Using Structural Allograft vs. Tritanium C

Recruiting
NAAges 18–80InterventionalBasic science
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
~60 participants
Updated 2026-08-31 on ClinicalTrials.gov
What's tested:Structural allograftTritanium C

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Time to the presence of fusion
Measured over 3 months post-operatively
+2 more outcomes measured
Degenerative Disc Disease

NCT04388332

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Allegheny Health Network

    Pittsburgh, Pennsylvaniastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Nestor Tomycz, MD · PRINCIPAL_INVESTIGATOR · Allegheny Health Network

Opens a ready-to-send draft in your own email app — review before sending.

  • Time to the presence of fusion3 months post-operatively

    Antero-posterior and lateral plain radiographs

  • Time to the presence of fusion6 months post-operatively

    Antero-posterior and lateral plain radiographs

  • Time to the presence of fusion12 months post-operatively

    Antero-posterior and lateral plain radiographs