HH2853 for Lymphoma and Advanced Solid Tumors
This study is testing a drug called HH2853 in people with certain types of lymphoma (FL Lymphoma, Peripheral T Cell Lymphoma) and advanced solid tumors. The main goals are to find the safest and most effective dose of HH2853, and to understand any side effects. HH2853 is given as tablets twice a day. The study is open to adults aged 18 and older. It's a multi-part study, starting with finding the right dose and then expanding to learn more about how well it works and its safety. The study aims to enroll 254 participants, but its current status is unclear.
- Study design
- This is an open-label (meaning everyone knows what treatment is being given), multi-center, first-in-human study with three parts: dose escalation, dose extension, and Phase II. It plans to enroll 254 participants.
- What's involved
- You would take HH2853 tablets twice daily in continuous 28-day treatment cycles. Safety and side effects will be checked during these cycles.
- Compensation
- Not stated in the trial record.
- Follow-up
- Safety and dose-related outcomes are measured during 28-day treatment cycles.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Evaluate the Safety and Clinical Activity of HH2853
At a glance
Conditions
Where it's being run
25 sites across 20 statesStudy leadership
- Fugen Li · STUDY_DIRECTOR · Haihe Biopharma Co., Ltd.
Who to contact
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What this trial measures
- Maximum tolerated Dose (MTD)28-day treatment cycles
Determine MTD of HH2853
- Recommended phase II dose (RP2D)28-day treatment cycles
Determine RP2D of HH2853
- Adverse events assessed according to NCI-CTCAE V5.028-day treatment cycles
Evaluate the safety of HH2853
- Dose limiting toxicities (DLT)28-day treatment cycles
Evaluate the tolerability of HH2853
- Objective response rate (ORR)28-day treatment cycles
Assess the preliminary efficacy of HH2853