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Fermented Food-Supplemented Diet for Ulcerative Colitis

This study is looking at how a diet supplemented with fermented foods, like kimchi, sauerkraut, yogurt, and kefir, affects inflammation and quality of life in people with mild to moderate Ulcerative Colitis (UC). Researchers want to understand if these foods can help reduce inflammation in the gut. You might be able to join if you are at least 18 years old, have a confirmed diagnosis of UC with active symptoms, and have elevated fecal calprotectin (a marker of inflammation). The study aims to see if there's a change in this inflammation marker after 10 weeks on the special diet compared to a regular diet. The current status of this study is unclear, and it plans to enroll 21 participants.

Study design
This interventional study plans to enroll 21 participants to compare a fermented food-supplemented diet with a regular diet.
What's involved
Participants will have their fecal calprotectin measured at the start of the study and again at Week 10.
Compensation
Not stated in the trial record.
Follow-up
Participants are followed for 10 weeks after starting the diet.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04401605

Fermented Food-Supplemented Diet in Ulcerative Colitis

Recruiting
NAAges 18+InterventionalTreatment
Stanford University
~21 participants
Updated 2026-02-27 on ClinicalTrials.gov
What's tested:Fermented Food-supplemented DietRegular Diet

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in the clinical disease activity inflammatory marker fecal calprotectin
Measured over Baseline (Data Collection 1) versus Week 10 (Data Collection 2).

Conditions

Inflammatory Bowel Diseases
Diet Modification
Ulcerative Colitis

Explore related trials

Ulcerative Colitis

Where it's being run

1 sites across 1 states
California1

Study leadership

  • Sidhartha Sinha, MD · PRINCIPAL_INVESTIGATOR · Stanford University

Who to contact

Touran Fardeen
[email protected]
6507367311
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Written informed consent
Male or female subjects, ≥18 years of age
Confirmed diagnosis of UC
Symptomatic disease defined as partial Mayo Score 2 to 7 (inclusive)
Elevated fecal calprotectin

Exclusion

Women who are pregnant, nursing or expect to be pregnant
Intolerance to fermented food
Individuals with a body mass index (BMI) lower than 18
Individuals diagnosed with a serious medical condition (unless approved in writing by a physician)
Individuals who have been severely weakened by a disease or medical procedure
Individuals with more than mild-moderate cardiovascular disease or life-threatening cancer (as determined by patient's physician) unless approved by a physician
Individuals with history of severe cardiac disease (particularly uncompensated congestive heart failure NYHA grade 2 or more or LVEF \< 40%)
History of relevant intestinal surgery such as total or hemi-colectomy, proctocolectomy, stoma.

What this trial measures

  • Change in the clinical disease activity inflammatory marker fecal calprotectinBaseline (Data Collection 1) versus Week 10 (Data Collection 2).

    Change in fecal calprotectin