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Rheumatology Patient Registry and Biorepository

This study is creating a collection of information and samples (a biorepository) from people with rheumatic diseases. The goal is to better understand these conditions, such as adult onset Still's disease, ankylosing spondylitis, and psoriatic arthritis. Researchers will look at how different factors relate to the long-term outcomes of these diseases over 10 years. You may be able to join if you are 18 to 99 years old and have been diagnosed with a rheumatic autoimmune disease at a Yale clinic. The study is currently collecting participants.

Study design
This is an observational study planning to enroll 5000 participants. It is not testing a specific drug or intervention.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants' outcomes will be measured for up to 10 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04402086

Rheumatology Patient Registry and Biorepository

Recruiting
Not specifiedAges 18–99Observational
Yale University
~5,000 participants
Updated 2026-02-13 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Correlate outcomes and biomarkers of rheumatic diseases
Measured over 10 years

Conditions

Rheumatic Diseases
Adult Onset Still Disease
Ankylosing Spondylitis
Psoriatic Arthritis
Reactive Arthritis
Antiphospholipid Syndrome
Systemic Lupus Erythematosus
Behcet Disease
Dermatomyositis
Polymyositis
Giant Cell Arteritis
Lyme Disease
Mixed Connective Tissue Disease
Polymyalgia Rheumatica
Rheumatoid Arthritis
Sarcoidosis
Systemic Sclerosis
Scleroderma
Sjogren's Syndrome
Undifferentiated Connective Tissue Diseases

Explore related trials

Adult-Onset Still's DiseaseAnkylosing SpondylitisAntiphospholipid SyndromeBehcet SyndromeBorrelia Burgdorferi InfectionDermatomyositisGiant Cell ArteritisMixed Connective Tissue DiseasePolymyalgia RheumaticaPolymyositisPsoriatic ArthritisReactive ArthritisRheumatismRheumatoid ArthritisSarcoidosisSjogren SyndromeSystemic Lupus ErythematosusSystemic SclerodermaUndifferentiated Connective Tissue Disease

Where it's being run

1 sites across 1 states
Connecticut1

Study leadership

  • Monique Hinchcliff, MD · PRINCIPAL_INVESTIGATOR · Yale University

Who to contact

Stephanie Perez, MS, BS
[email protected]
203-737-5571
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patients ≥18 years old with a diagnosis of a rheumatic autoimmune disease including, but not limited to: adult onset Still's disease, ankylosing spondylitis, antiphospholipid syndrome, Behcet's disease, dermatomyositis, giant cell arteritis, mixed connective tissue disease, polymyalgia rheumatica, polymyositis, psoriatic arthritis, reactive arthritis, rheumatoid arthritis, sarcoidosis, scleroderma, Sjogren's syndrome, systemic lupus erythematosus, undifferentiated connective tissue disease and vasculitis.
Receiving clinical care at Yale Rheumatology clinics
Age ≥ 18 years old
No chronic skin conditions
No diagnosis of a rheumatic autoimmune disease (e.g., lupus, rheumatoid arthritis)
Normal BMI

Exclusion

Unable to provide informed consent
No patients will be excluded based on gender or ethnicity or pregnancy status.
Women who are currently pregnant will need to wait to donate a skin biopsy until after they deliver.
Patients allergic to lidocaine or epinephrine or have a history of impaired wound healing will not be able to donate a skin biopsy.
Unable to provide informed consent.
Currently pregnant or nursing unless the study goal is to study pregnant or nursing woman.
Allergies to lidocaine or epinephrine (skin biopsies).
A history of impaired wound healing (skin biopsies).

What this trial measures

  • Correlate outcomes and biomarkers of rheumatic diseases10 years

    Evaluate clinical data and biospecimens to correlate outcomes and biomarkers of rheumatic diseases.