Observational Study of EUS-Guided Celiac Plexus Neurolysis for Chronic Pancreatitis Pain
This study is looking at how well a procedure called Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) helps manage pain for people with chronic pancreatitis. Chronic pancreatitis causes severe abdominal pain, and current pain medications like opioids can have side effects. EUS-CPN involves injecting alcohol into nerves near the pancreas to temporarily or semi-permanently block pain signals. The study wants to track the impact of this procedure on your pain levels and how much pain medication you use. You might be able to join if you are 18 or older and have pain from chronic pancreatitis. The study will measure your pain intensity and medication use for up to 24 weeks after the procedure.
- Study design
- This is an observational study planning to enroll 35 participants. It is not a randomized or blinded study, meaning all participants will receive the Celiac Plexus Neurolysis procedure if a Celiac Plexus Block is not effective.
- What's involved
- You would have a Celiac Plexus Neurolysis procedure if a Celiac Plexus Block doesn't provide enough pain relief. Your pain intensity and medication use would be assessed immediately after the procedure and then weekly for up to 24 weeks via phone calls.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 24 weeks after the Celiac Plexus Neurolysis procedure, with weekly assessments of pain and medication use.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Mo A, MD · PRINCIPAL_INVESTIGATOR · Indiana University
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Use of Pain medicationImmediately post procedure & weekly up to 24 weeks
Use of pain medication (by using morphine equivalents) for each patient will be tracked weekly for up to 24 weeks post CPN to track pain management/relief for the of patients. There should be a lessening in use of pain medication as time progesses.
- Patient's pain intensity score (numeric pain rating scale using the visual analogue scale VAS from 1-10) will be assessed weekly (via phone call follow ups) starting right after CPN and continuing for 24 weeks.Immediately post procedure and weekly up to 24 weeks
Compare weekly pain intensity score for pain management/relief of patients.
- Dosage of pain medicationImmediately post procedure and weekly up to 24 weeks
Compare dose of pain medication post procedure \& weekly for up to 24 weeks after converting all to morphine equivalents