Lumbar Interbody Implant Study for Degenerative Spinal Conditions

This study is looking at the safety and performance of NuVasive interbody implants, which are used during spine surgery. It aims to understand how well these implants work and if there are any risks over time. You might be able to join if you are at least 18 years old and are planning to have spine surgery for conditions like degenerative disc disease, degenerative spondylolisthesis (when a bone in your spine slips forward), degenerative scoliosis (a curve in the spine), or spinal stenosis (narrowing of the spinal canal). The study will measure success by looking at complications and how well the bones fuse together after 24 months. The current status of this study is unclear.

Study design
This is an observational study, meaning researchers will watch and collect information from patients undergoing standard surgery. It plans to enroll at least 1050 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 24 months after surgery to check for complications and fusion success.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04418830

Lumbar Interbody Implant Study

Enrolling by Invitation
Not specifiedAges 18+Observational
NuVasive
~1,050 participants
Updated 2025-12-22 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 16 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Complications of Interbody Implants
Measured over 24 months
+1 more outcome measured
Degenerative Disc Disease
Degenerative Spondylolisthesis
Degenerative Scoliosis
Spinal Stenosis
Sagittal Deformity

NCT04418830

Where you'd take part

This study runs at 16 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Atlantic Brain and Spine

    Wilmington, North Carolinano site contact published

  • Beaumont Hospital Research Institute

    Royal Oak, Michiganno site contact published

  • Columbia Orthopaedics Group

    Columbia, Missourino site contact published

  • Duke University

    Durham, North Carolinano site contact published

  • DuPage Medical Group

    Naperville, Illinoisno site contact published

  • Hartford Healthcare Bone and Joint Institute

    Hartford, Connecticutno site contact published

  • Hoag Orthopedics

    Orange, Californiano site contact published

  • Lyerly Neurosurgery

    Jacksonville, Floridano site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Kyle Malone, MS · STUDY_DIRECTOR · Globus Medical

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Complications of Interbody Implants24 months

    Rate of complications attributable to the use of the interbody implants to be studied

  • Radiographic Fusion Success24 months

    The proportion of subjects with apparent radiographic fusion at or before 24 months within each treatment group