This observational study is looking at how the ovaries develop in adolescent girls after their first period (menarche). Researchers want to understand if the size and number of follicles (small sacs in the ovaries that hold eggs) can predict whether a girl will have regular or irregular periods later on. They are also exploring if diet or sleep habits affect these changes. This study aims to help identify conditions like polycystic ovary syndrome (PCOS) earlier. Girls aged 9 to 17 who have had their first period within the last 11 months can join. For those at the University of Rochester site, a family history of PCOS (mother or aunt) is also required. The study will measure ovarian size, follicle counts, and menstrual cycle status over 24 months.

Study design

This is an observational study involving up to 60 female adolescents. It is not a drug trial, but rather observes natural changes over time.

What's involved

You would attend four study visits over approximately 24 months. Before each visit, you would complete a 24-hour dietary recall and provide a stool sample, and fast overnight.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for 24 months, with primary measurements taken at the end of this period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.