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Targeted TDCS for Post-Stroke Aphasia

This study is looking at whether a treatment called cathodal tDCS (transcranial direct current stimulation) can improve speech and language therapy for people who have aphasia (difficulty with language) after a stroke. You might be able to join if you are between 25 and 85 years old, had a stroke more than six months ago, and have aphasia that affects the left side of your brain. The study will compare cathodal tDCS combined with language training to language training alone (using a sham, or inactive, tDCS device). Researchers will measure how well participants can name pictures and how quickly and efficiently they can name things after three months to see if the treatment is successful. The current recruitment status is unclear.

Study design
This is an interventional study planning to enroll 50 participants. It compares an active treatment (cathodal tDCS plus language training) to a placebo (sham tDCS plus language training).
What's involved
Participants will have 4 assessment sessions and 15 treatment sessions. Two assessments are before treatment, one immediately after, and one at 3 months follow-up.
Compensation
Not stated in the trial record.
Follow-up
Participants will have a follow-up assessment 3 months after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04432883

Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.

Recruiting
NAAges 25–85InterventionalTreatment
University of New Mexico
~50 participants
Updated 2026-05-22 on ClinicalTrials.gov
What's tested:Active Comparator: Experimental: Active cathodal tDCS + language trainingSham Comparator: Placebo cathodal tDCS + Speech and language

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Picture Naming of trained items
Measured over 3 months
+2 more outcomes measured

Conditions

Stroke
Aphasia

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AphasiaStroke

NCT04432883

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of New Mexico Center for Brain Recovery and Repair

    Albuquerque, New Mexicostudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Jessica Richardson, Ph.D. · PRINCIPAL_INVESTIGATOR · University of New Mexico

Who to contact

Jessica Richardson, Ph.D.
[email protected]
505 277-1765
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

What this trial measures

  • Picture Naming of trained items3 months

    Change in naming of pictures of trained items; 60 pictured items; higher score indicates improvement

  • Naming Response Time of trained items Scales - IV (WAIS-IV; Wechsler, Coalson, & Railford, 2008)3 months

    Change in response time of naming of pictures of trained items; 0-20 seconds, decreased response time indicates improvement Scales - IV (WAIS-IV; Wechsler, Coalson, \& Railford, 2008)

  • Naming Efficiency of trained items3 months

    Change in efficiency of naming of pictures of trained items; median response time divided by proportion correct naming; smaller numbers indicate greater efficiency