iPhone Weight Management App for Adolescents and Young Adults After Stem Cell Transplant

This study is looking at whether an iPhone app called W8Loss2Go, combined with coaching, can help adolescents and young adults (ages 13-30) lose weight after a stem cell transplant (HSCT). You could join if you've had a stem cell transplant at least 100 days ago, are classified as obese (BMI >= 85th percentile for your age and gender), and can read English. The study aims to see how well this app and coaching help with weight loss, measured by changes in your body mass index (BMI) over 12 months. Researchers also want to learn more about healthy eating habits and how this intervention affects your metabolism and physical activity. The current recruitment status is unclear.

Study design
This is an interventional study with a planned enrollment of 20 participants. It is an early phase I trial, meaning it's one of the first times this intervention is being studied.
What's involved
You would receive an iPhone with the W8Loss2Go app, a body scale, and a food scale. You would interact with coaches via text messages four days a week and have weekly 15-minute phone calls, plus longer telemedicine interviews at 2 and 4 months.
Compensation
Not stated in the trial record.
Follow-up
Your body mass index (BMI) status will be measured at the beginning of the study and up to 12 months later.

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NCT04453072

A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

Recruiting
NAAges 13–30InterventionalSupportive care
Jonsson Comprehensive Cancer Center
~20 participants
Updated 2026-05-11 on ClinicalTrials.gov
What's tested:InterviewMedia InterventionQuestionnaire AdministrationScale DeviceTelephone-Based InterventionText Message

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in body mass index (BMI) status
Measured over Baseline up to 12 months
Obesity
Malignant Neoplasm
1 sites across 1 states
California1
  • Theodore B Moore · PRINCIPAL_INVESTIGATOR · UCLA / Jonsson Comprehensive Cancer Center

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Eligibility criteria

Inclusion

Patients with a history of HSCT of any type, at least 100 days post-transplant at initial consultation of the study, will be eligible for the study
Patients must classify as obese, represented as body mass index (BMI) \>= 85th percentile for age and gender
Patients must also be able to read English since the app intervention is only available in English form
No patients will be excluded for any specific underlying medical condition, but decisions will be made on a case by case basis if a patient's functioning is deemed to significantly interfere with intervention participation
PARENT:
\>= 18 years of age
Can speak English

Exclusion

Patients who are \< 100 days post-transplant at initial consultation will not be eligible for the study, but may become eligible if they are \> 100 days post-transplant at their next consultation that falls within the enrollment window
Patients whose BMI does not fall under the obese category will be excluded
  • Change in body mass index (BMI) statusBaseline up to 12 months

    The main outcomes measures will be height (meters), weight (kg), and BMI (kg/m\^2). Height will be measured to assess consistency in height measurements. Weight will be measured to assess trends in weight over the time span of the intervention. BMI will be measured as a product of weight and height to obtain an appropriate metric that accounts for these measures, and is the standard measure to assess weight progression in weight intervention studies.