Understanding Atopic Dermatitis Severity and the IL-4Ra R576 Polymorphism
This study is looking into whether a specific genetic difference, called the IL-4Ra R576 polymorphism, is linked to more severe atopic dermatitis (a type of eczema). Researchers want to see if this genetic difference is connected to changes in your body's immune system and the types of microbes on your skin. You can join if you are 6 to 65 years old and have atopic dermatitis. The study will measure the severity of your atopic dermatitis at the beginning of the study. The current recruitment status is unclear.
- Study design
- This is an observational study, meaning researchers will observe participants without providing any specific intervention. It plans to include 111 participants.
- What's involved
- You would have one visit where questionnaires, a blood draw, a skin swab, and skin biopsies would be performed.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Mechanisms of Increased Disease Severity in AD Patients With the IL-4Ra R576 Polymorphism
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Wanda Phipatanakul, MD. MS. · PRINCIPAL_INVESTIGATOR · Boston Children's Hospital
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- atopic dermatitis severitybaseline, only 1 time point
validated assessment EASI score