Impact of Sinus Surgery on Individuals With Cystic Fibrosis
This observational study is looking at how sinus surgery affects adults with cystic fibrosis (CF) and chronic rhinosinusitis (CRS), which is ongoing inflammation of the sinuses. Researchers want to understand if endoscopic sinus surgery helps improve lung function and reduce hospital stays. You could be eligible if you are between 18 and 99 years old, have a confirmed diagnosis of CF, and have chronic rhinosinusitis. The study will compare people who have sinus surgery with those who receive medical treatment for CRS. Success will be measured by changes in lung function and the number of days spent in the hospital over 12 months. The current recruitment status is unclear, but the study plans to enroll 170 participants.
- Study design
- This is an observational study comparing people who have endoscopic sinus surgery for chronic rhinosinusitis with those who receive medical treatment. It plans to include 170 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 12 months after starting the study.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Impact of Sinus Surgery on Individuals With Cystic Fibrosis
At a glance
Conditions
Where it's being run
9 sites across 7 statesStudy leadership
- Daniel M Beswick, MD · PRINCIPAL_INVESTIGATOR · University of California, Los Angeles
Who to contact
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What this trial measures
- Change in pulmonary functionbaseline, 3, 6, 9, 12 months
Pulmonary function will be measured using spirometry - the percent of predicted forced expiratory volume in the first second (ppFEV1)
- Change in days of inpatient hospitalizationbaseline, 3, 6, 9, 12 months
Days of inpatient hospitalization will be assessed