Back to search results

Study on Interrupting Sitting for Type 2 Diabetes Prevention in Children

This study is looking at how interrupting sitting with activity affects children who are at risk for type 2 diabetes. We want to see if taking short breaks from sitting (SIT+WALK) or doing one longer exercise session (EX) can improve health markers like blood sugar and insulin levels. You might be able to join if you are 8-11 years old, in good general health, and have a BMI (Body Mass Index) at or above the 85th percentile. The main goal is to measure changes in your blood sugar and insulin levels over three hours, from the beginning to the end of a one-week period. The current status of this study is unclear, and it plans to enroll 188 participants.

Study design
This is an interventional study, meaning participants will receive specific activities. It plans to enroll 188 participants.
What's involved
Participants will either interrupt their sitting for one week (SIT+WALK) or perform a single bout of exercise and then sit for the remaining time for one week (EX). Blood samples will be taken at specific times over 3 hours on Day 1 and Day 7.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for changes in blood sugar and insulin levels from Day 1 to Day 7.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04469790

Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children

Active, Not Recruiting
NAAges 8–11InterventionalPrevention
University of Southern California
~188 participants
Updated 2026-06-15 on ClinicalTrials.gov
What's tested:SIT+WALKEX

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
In-Lab glucose area under the curve (AUC)
Measured over 3 hours (-10, 0, 30, 60, 90, 120, 150, 180 minutes) AUC change from Day 1 to Day 7
+3 more outcomes measured

Conditions

Sedentary Behavior
Affect
Metabolic Disturbance
Anxiety
Cardiac Autonomic Nervous System Function

Explore related trials

ObesityOverweight

Where it's being run

1 sites across 1 states
California1

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

What this trial measures

  • In-Lab glucose area under the curve (AUC)3 hours (-10, 0, 30, 60, 90, 120, 150, 180 minutes) AUC change from Day 1 to Day 7

    change in glucose AUC from oral glucose tolerance tests

  • In-Lab insulin area under the curve (AUC)3 hours (-10, 0, 30, 60, 90, 120, 150, 180 minutes) AUC change from Day 1 to Day 7

    change in insulin AUC from oral glucose tolerance tests

  • In-Lab c-peptide area under the curve (AUC)3 hours (-10, 0, 30, 60, 90, 120, 150, 180 minutes) AUC change from Day 1 to Day 7

    change in c-peptide AUC from oral glucose tolerance tests

  • Continuous glucose monitor measures7 days

    mean daily 24-hr glucose area under the curve (AUC)