Understanding Young Onset Colorectal Cancer

This study is collecting information to better understand colorectal cancer (cancer of the colon or rectum) that is diagnosed in younger individuals (before age 50). Researchers are creating a database of information from patients with young onset colorectal cancer. You may be able to participate if you have been diagnosed with gastrointestinal cancer and are between 18 and 49 years old. The main goal is to build this database over one year to help researchers learn how young onset colorectal cancer might be similar to or different from colorectal cancer diagnosed later in life, and to support future research.

Study design
This is an observational study, meaning researchers will collect information without giving any specific treatments. It plans to enroll 1366 participants.
What's involved
Participants will complete a risk factor questionnaire, preferably at their first visit.
Compensation
Not stated in the trial record.
Follow-up
The primary goal is to establish a database over one year.

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NCT04489238

Collection of Information to Better Understand Young Onset Colorectal Cancer

Recruiting
Not specifiedAges 18+Observational
Memorial Sloan Kettering Cancer Center
~1,366 participants
Updated 2026-02-06 on ClinicalTrials.gov
What's tested:Risk Factor Questionnaire

At a glance

Recruiting sites
8 of 8 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Establish a prospective database of patients with Young Onset Colorectal Cancer
Measured over 1 year
Colorectal Cancer
Colorectal Carcinoma
8 sites across 2 states
New York5
New Jersey3
  • Andrea Cercek, MD · PRINCIPAL_INVESTIGATOR · Memorial Sloan Kettering Cancer Center

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Histological or cytological diagnosis of gastrointestinal cancer
18 - 49 years old at time of consent
No Known hereditary CRC or other cancer predisposition syndrome (stool collection cohort only)
No history of inflammatory bowel disease (stool collection cohort only)
No prior diagnosis of gastrointestinal cancer (stool collection cohort only)
Histological or cytological diagnosis of colorectal adenocarcinoma
No previous treatment for CRC (including surgery, chemotherapy, immunotherapy or radiation)
Age 50 or older at time of consent
No Known hereditary CRC or other cancer predisposition syndrome
No history of inflammatory bowel disease
No prior diagnosis of CRC
  • Establish a prospective database of patients with Young Onset Colorectal Cancer1 year

    from diagnosis through survivorship