The Hepatitis C Transplant Collaborative
This study is looking at the safety and outcomes for people who receive a heart transplant from a donor who had hepatitis C (HCV NAT+ donor organs). Researchers want to see if using these donor hearts, along with new treatments for hepatitis C, leads to good results for patients. You could join if you are 18 or older and have received a heart from a donor who tested positive for hepatitis C. This includes people who are having a re-transplant. The study will measure how many people get a heart transplant from an HCV NAT+ donor, how many are cured of hepatitis C, and the rate of primary graft dysfunction (when the new heart doesn't work well right away). The study is currently unclear on its status and plans to enroll 500 participants.
- Study design
- This is an observational study, meaning researchers will watch and collect information without giving specific treatments. It plans to include 500 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for up to 6.5 years to assess cure rates and for 30 days to assess primary graft dysfunction.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
The Hepatitis C Transplant Collaborative
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Shelley A Hall, MD FACC · PRINCIPAL_INVESTIGATOR · BSWRI
Who to contact
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What this trial measures
- Number of donor HCV nucleic-acid testing positive (HCV NAT+) cardiac transplantation6.5 years
To assess the current status of donor HCV NAT+ cardiac transplantation via retrospective data collection.
- Failure versus Cure Rate for HCV NAT+ Heart Transplants6.5 years
sustained viral response (SVR)-12 (cure-rate) for HCV negative recipient
- Rate of Primary graft dysfunction (PGD)30 days
Rate of Expected Post-Transplant Risks
- 1 year mortality1 Year
Number of deaths
- Cellular graft rejection rate6.5 years
Graft rejection rate
- Antibody Mediated Rejection rate6.5 years
Graft rejection rate