Observational Study of Esophageal Tests for Dysphagia

This observational study is looking at people who have difficulty swallowing (dysphagia) and a known esophageal diagnosis. Researchers are comparing two common diagnostic tests: esophageal manometry-impedance and the Endolumenal Functional Lumen Imaging Probe (EndoFLIP). Both tests measure different aspects of how your esophagus (the tube that carries food to your stomach) works. The goal is to understand how the results from these tests relate to each other and to your symptoms. You can participate if you are between 18 and 99 years old and have already had or are scheduled for these tests at the GI Motility Lab at IU University Hospital. The study aims to create a registry of information from these tests over five years.

Study design
This is an observational study with a planned enrollment of 1000 participants. It is not a treatment study but rather collects information from existing diagnostic tests.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, Endoflip parameters for gastroparesis, will be measured at 5 years.

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NCT04503785

Esophageal Impedance and Manometry Measurements and Dysphagia Symptom Scoring

Recruiting
Not specifiedAges 18–99Observational
Indiana University
~1,000 participants
Updated 2026-06-16 on ClinicalTrials.gov
What's tested:Manometry

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Endoflip parameters for gastroparesis
Measured over 5 years
Dysphagia, Esophageal
1 sites across 1 states
Indiana1
  • John M Wo, MD · PRINCIPAL_INVESTIGATOR · Indiana University

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Eligibility criteria

Inclusion

All patients who presented to GI Motility Lab at IU University Hospital for esophageal manometry-impedance and/or EndoFLIP

Exclusion

Age \<18 yrs old
Unable to communicate verbally with the staff
  • Endoflip parameters for gastroparesis5 years

    Compare the distensibility index (mm2/mmHg) of the pylorus at 50 ml distension in patients with postsurgical gastroparesis and compare to patients with idiopathic and diabetic gastroparesis.