Biospecimen Collection Study for Cancer

This study is collecting tumor samples and health information from people with certain cancers, including head and neck, lung, and urothelial carcinoma (bladder cancer). Researchers are using these samples to develop and test a diagnostic tool called OncoPrism™. This tool looks at specific markers (PD-1, PD-L1) in tumor tissue to understand how well people might respond to PD-1/PD-L1 inhibitor treatments. The goal is to see how well these markers predict a response to treatment after 6 months. The study is currently unclear on its recruitment status.

Study design
This is an observational study planning to enroll 1650 participants. It collects de-identified tumor samples and clinical data.
What's involved
You would provide consent for your tumor samples and health information to be used. The study does not require extra biopsies; standard-of-care biopsies taken before immunotherapy are used.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint measures PD-L1/PD-1 inhibitor response at 6 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04510129

A Multicenter Cancer Biospecimen Collection Study

Recruiting
Not specifiedAges 18+Observational
Cofactor Genomics, Inc.
~1,650 participants
Updated 2025-03-12 on ClinicalTrials.gov
What's tested:OncoPrism™ assay

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
PD-L1/PD-1 inhibitor response
Measured over 6 months
Cancer of Head and Neck
Lung Cancer, Nonsmall Cell
Small-cell Lung Cancer
Urothelial Carcinoma
Gastroesophageal Junction Adenocarcinoma
Cervical Cancer
Esophageal Squamous Cell Carcinoma
Triple Negative Breast Cancer
Hepatocellular Carcinoma
Renal Cell Carcinoma
Colorectal Cancer
1 sites across 1 states
California1
  • Jarret Glasscock · STUDY_DIRECTOR · Cofactor Genomics

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  • PD-L1/PD-1 inhibitor response6 months

    No response to treatment with PD-L1/PD-1 inhibitor and response to treatment with PD-L1/PD-1 inhibitor.