Phase II Panitumumab-IRDye800 in Head & Neck Cancer

This study is testing a drug called panitumumab-IRDye800 to see how well it helps doctors find head and neck cancer during surgery. The drug works as a monoclonal antibody, which means it's designed to target specific cells. Researchers want to see if panitumumab-IRDye800 can make cancer cells glow, making them easier to see compared to healthy tissue. They will also be looking at the safety of this drug. You may be able to join if you are an adult with squamous cell carcinoma (a type of cancer) of the head and neck that requires surgery. The study aims to enroll 25 participants.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 25 participants.
What's involved
Participants will receive a single dose infusion of panitumumab-IRDye800CW. Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The study will measure the tumor to background ratio of fluorescence from Day 0 through Day 15 after receiving the drug.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04511078

Phase II Panitumumab-IRDye800 in Head & Neck Cancer

Recruiting
PHASE2Ages 18+InterventionalDiagnostic
University of Alabama at Birmingham
~25 participants
Updated 2025-12-24 on ClinicalTrials.gov
What's tested:Panitumumab-IRDye800

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Tumor to background ratio of fluorescence (TBR)
Measured over Day 0 through Day 15
Head and Neck Cancer
1 sites across 1 states
Alabama1
  • Anthony Morlandt, DDS MD · PRINCIPAL_INVESTIGATOR · University of Alabama at Birmingham

Opens a ready-to-send draft in your own email app — review before sending.

  • Tumor to background ratio of fluorescence (TBR)Day 0 through Day 15

    fluorescence intensity of tumor tissue compared to that of normal surrounding tissue