This study is looking at how a drug called 5-Hydroxytryptophan (5-HTP), combined with Carbidopa, affects people with spinal cord injuries. Researchers want to see if these drugs change how your nervous system responds and how well your muscles work. You might be able to join if you are between 18 and 65 years old and had a spinal cord injury at least six months ago. The study aims to understand if these drugs can improve muscle activation and movement. The current status of this study is unclear.

Study design

This is a randomized, double-blinded, placebo-controlled crossover study involving 30 participants. This means participants will receive different treatments, including a placebo, without knowing which one they are getting.

What's involved

Participants will visit the lab on 4 separate occasions. During these visits, different drugs will be given, and measurements of nerve and muscle function will be taken.

Compensation

Not stated in the trial record.

Follow-up

Measurements will be taken at pre-drug intake, and then 30, 60, 90, and 120 minutes after drug intake on each visit.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.