Room Light and Labor Progression in Pregnancy

This study is looking at how different room lighting (Room light/light bulb) might affect uterine contractions (the tightening of your womb) and how labor progresses during pregnancy. Researchers believe that reducing or eliminating light in the evening and night could help your body naturally release melatonin, which might encourage contractions in late pregnancy. The study aims to see if changing room light can help achieve a vaginal birth and reduce the need for C-sections. You may be able to join if you are pregnant, between 18 and 42 years old, and medically cleared. The study is currently unclear on its recruitment status and plans to enroll 100 participants.

Study design
This is an interventional study with a planned enrollment of 100 pregnant women, aged 18-42 years.
What's involved
You would be recruited during your first trimester, provide saliva samples at home at specific times, and complete questionnaires. You would also need to report on lighting conditions.
Compensation
Not stated in the trial record.
Follow-up
Your uterine contractions will be measured from confirmation of pregnancy until birth, with the study time frame up to 40 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04521972

Impact of Room Light on Uterine Contractions and Labor Progression in Pregnancy

Recruiting
NAAges 18–42InterventionalBasic science
Michigan State University
~100 participants
Updated 2025-09-18 on ClinicalTrials.gov
What's tested:Room light/light bulb

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Nocturnal room light changes uterine contractions in pregnant women
Measured over From confirmation of pregnancy till birth. The study time frame is up to 40 weeks.
Pregnancy Related
Labor; Poor
Uterine Contractions Weak
1 sites across 1 states
Michigan1
  • Hanne M Hoffmann, PhD · PRINCIPAL_INVESTIGATOR · Michigan State University

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Eligibility criteria

Inclusion

Are pregnant
Are 18-42 years old
Medically cleared for participation by Medical Investigator
Willingness to allow the study access to information in the participant's medical record
Willingness to be notified of incidental findings from study procedures
Willingness to measure and report on lighting conditions during specified time periods
Willingness to use a uterine contraction home monitor system, and report results
Willingness to adapt lighting during studies in home and/or hospital
Willingness to wear blue-filter glasses if requested
Willingness to report use of melatonin (for sleep)
Willingness to stop melatonin use if requested

Exclusion

Pre-pregnancy BMI \>36kg/m2
HIV or AIDS (self-reported)
Severe anemia (hemoglobin \<8g/dL and/or hematocrit \<24%)
History or current psychotic disorder or diagnosis of a current major depressive episode or bipolar disorder
Current use of one or more of the following medications: metformin, systemic steroids, antipsychotic agents (e.g., Abilify, Haldol, Risperdal, Seroquel, Zyprexa), anti-seizure medications or mood stabilizers that would be expected to have a significant impact on body weight (e.g., Depakote, Lamictal, Lithium, Neurontin, Tegretol, Topamax, Keppra), medications for ADHD including amphetamines and methylphenidate
Recent history of or currently smoking, drinking alcohol or abusing drugs (prescription or recreational)
Plans to move out of the study area within the next year or plans to be out of the study area for more than 8 weeks in the next 12 months
Planned termination of pregnancy
  • Nocturnal room light changes uterine contractions in pregnant womenFrom confirmation of pregnancy till birth. The study time frame is up to 40 weeks.

    We will measure how room light during day and night periods impact uterine contractions during pregnancy and labor.