Recovery From Cushing Syndrome and Mild Autonomous Cortisol Secretion (MACS)

This study is looking at how people recover after surgery for Cushing Syndrome (CS), a condition where your body has too much of a hormone called cortisol. It also includes people with Mild Autonomous Cortisol Secretion (MACS). Researchers want to understand what factors, both before and after surgery, affect how quickly and completely people recover. They are also looking at how symptoms improve and if a technique called MUSE biofeedback, which uses a headband, can help with recovery. The study aims to enroll 700 adults, aged 18 and older, who have a new diagnosis of CS or MACS and are planning to have surgery to treat it. The main goal is to measure your quality of life using a survey over a period of up to 24 months.

Study design
This is an observational study, meaning researchers will watch and collect information from 700 participants. It is not a randomized trial.
What's involved
You would provide informed consent, and researchers would review your medical records and conduct interviews. Data collection will occur at periodic intervals for up to 24 months.
Compensation
Not stated in the trial record.
Follow-up
Your quality of life will be measured periodically for up to 24 months after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04543253

Recovery From Cushing Syndrome and Mild Autonomous Cortisol Secretion (MACS)

Recruiting
Not specifiedAges 18+Observational
Mayo Clinic
~700 participants
Updated 2025-09-03 on ClinicalTrials.gov
What's tested:MUSE biofeedback

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Quality of life (SF36)
Measured over periodic 0-24 months
Cushing Syndrome

NCT04543253

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Mayo Clinic

    Rochester, Minnesotastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Irina Bancos, MD, MS · PRINCIPAL_INVESTIGATOR · Mayo Clinic

Opens a ready-to-send draft in your own email app — review before sending.

  • Quality of life (SF36)periodic 0-24 months

    Score 0-100