Understanding Genetics for Men at Risk for Prostate Cancer

This study aims to understand how African American and rural White men at risk for localized prostate cancer (cancer that hasn't spread) understand genetic information related to their prognosis (the likely course of a disease). The study uses focus groups to explore how men comprehend this genetic technology. Researchers will also look at how an educational video about genetics affects how patients and caregivers talk about genetic information. The goal is to make sure that new genetic information helps all men with prostate cancer, especially those who might face health disparities. This study is currently unclear on its recruitment status and plans to enroll 90 participants.

Study design
This is an interventional study that will enroll 90 participants. It uses focus group analyses to understand genetic literacy.
What's involved
You would participate in focus group discussions. Your genetic literacy will be measured at baseline, before an intervention, and immediately after the intervention.
Compensation
Not stated in the trial record.
Follow-up
Genetic literacy is measured at baseline, pre-intervention, and immediately after the intervention. No further follow-up is specified.

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NCT04550845

Understanding of Genetics by Men at Risk for Prostate Cancer

Recruiting
NAAges 40–95InterventionalHealth services
Mayo Clinic
~90 participants
Updated 2025-11-06 on ClinicalTrials.gov
What's tested:Focus group analyses

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Estimate Genetic Literacy
Measured over Baseline
+5 more outcomes measured
Prostate Cancer
3 sites across 3 states
Arizona1
Florida1
Minnesota1
  • Ewan K Cobran, PhD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

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Eligibility criteria

Inclusion

African-American or White men
Living in a rural or urban areas
Age 40 to 95 years old
Able and willing to provide informed consent
English-speaking
Willing to participate in the study.
  • Estimate Genetic LiteracyBaseline

    The Rapid Estimate of Adult Literacy in Genetic - Short Form: An 8-item measure to asses adult literacy in genetics will be used.

  • Estimate Genetic LiteracyPre-intervention

    The Rapid Estimate of Adult Literacy in Genetic - Short Form: An 8-item measure to asses adult literacy in genetics will be used.

  • Estimate Genetic LiteracyImmediately after the intervention

    The Rapid Estimate of Adult Literacy in Genetic - Short Form: An 8-item measure to asses adult literacy in genetics will be used.

  • Prostate Cancer Genetic UnderstandingBaseline

    The Prostate Cancer Genetic Literacy Application (PCGLA) Educational Video, which was developed for this research, will be used as the study educational intervention. Prostate Cancer Genetic understanding will be assess with an 18-item knowledge prostate cancer genetic survey. The items are True or False.

  • Focus Group DiscussionBaseline

    A semi-structured focus group discussion about the Prostate Cancer Genetic Literacy Application (PCGLA) educational video.

  • Focus Group DiscussionImmediately after the intervention

    A semi-structured focus group discussion about the Prostate Cancer Genetic Literacy Application (PCGLA) educational video.