This study is testing a new treatment called Low-Intensity Focused Ultrasound Pulsation (LIFUP) for people with moderate to severe Generalized Anxiety Disorder (GAD), a condition causing excessive worry. LIFUP aims to treat anxiety by targeting deep brain areas like the amygdala, which current treatments like rTMS cannot reach. You might be eligible if you are 18-65 years old, have been diagnosed with GAD for over a year, and have a Hamilton Anxiety Rating Scale (HAM-A) score above 17. The study will involve 48 participants who will receive either active LIFUP treatment or a sham (inactive) treatment over eight sessions. Researchers will measure changes in your anxiety using the HAM-A scale one week after the fourth treatment to see if LIFUP is effective. The current status of this study is unclear.

Study design

This is a double-blind, sham-controlled study, meaning neither you nor the researchers will know if you are receiving the active LIFUP treatment or the sham treatment. It plans to enroll 48 participants.

What's involved

You would receive eight LIFUP treatments over four sessions. Your anxiety levels will be assessed after each session and at follow-up appointments.

Compensation

Not stated in the trial record.

Follow-up

You will have follow-up evaluations one week and one month after your last treatment session.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.