This study is looking at whether using a V-care® intrauterine manipulator during surgery for early-stage endometrial cancer (cancer of the lining of the uterus) might increase the chance of finding cancer cells in the fluid around the organs in your belly (positive peritoneal cytology). Endometrial cancer is common, and while most cases are found early, some patients experience recurrence. Researchers want to see if positive peritoneal cytology, which has been linked to worse outcomes, is more common when a V-care® intrauterine manipulator is used compared to a sponge stick during surgery. You may be able to join if you are 18 or older, have been diagnosed with endometrial cancer by biopsy, are planning standard surgery for early-stage endometrial cancer, and do not have signs of widespread cancer in your belly. The study will measure positive peritoneal cytology after 2 years.

Study design

This is an interventional study planning to enroll 350 women. It compares two surgical tools used during endometrial cancer surgery.

What's involved

Patients will undergo standard surgical staging for endometrial cancer, using either a V-care uterine manipulator or a sponge stick.

Compensation

Not stated in the trial record.

Follow-up

The primary outcome, conversion of positive peritoneal cytology, will be measured at 2 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.