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Mobile Low-dose CT Screening for Lung Cancer in Ages 40-54

This study is looking at whether mobile low-dose computed tomography (LDCT) screening can help find lung cancer in people aged 40-54. LDCT is a special type of X-ray that takes detailed pictures of your lungs. Previous studies have shown that LDCT screening helps people aged 55 and older with a strong smoking history live longer. However, some people develop this smoking history before they reach age 55. This study aims to see if screening at a younger age (40-54) can help detect lung cancer earlier in this high-risk group. The main goal is to see how many lung cancer diagnoses are made in this age group after their first mobile LDCT screening.

Study design
This is an interventional study planning to enroll 1160 participants. It is not specified if it is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, lung cancer diagnosis rate, is measured at 1 day after the first screening. Secondary objectives include evaluating rates at subsequent screening visits (T1 and T2).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04577599

Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54

Recruiting
NAAges 40–54InterventionalScreening
Wake Forest University Health Sciences
~1,160 participants
Updated 2026-07-13 on ClinicalTrials.gov
What's tested:Mobile Low-dose Computed Tomography (LDCT) Screening

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Lung cancer diagnosis rate in individuals 40-54 years of age at their first screening (T0) with mobile low-dose CT.
Measured over 1 day

Conditions

Lung Neoplasms
Lung Cancer

Explore related trials

Lung Carcinoma

Where it's being run

1 sites across 1 states
North Carolina1

Study leadership

  • Daniel Carrizosa, MD · PRINCIPAL_INVESTIGATOR · LCI

Who to contact

Darcy Doege, RN
[email protected]
913-424-6431
Email the study team

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Eligibility criteria

Exclusion

Subjects meeting any of the criteria below may not participate in the study:

What this trial measures

  • Lung cancer diagnosis rate in individuals 40-54 years of age at their first screening (T0) with mobile low-dose CT.1 day

    The lung cancer diagnosis variable will be determined for each subject as a binary variable indicating whether or not the subject's T0 screening results in a diagnosis of lung cancer.