Tamsulosin for Urinary Retention After Pelvic Surgery

This study is looking at whether a medication called Tamsulosin can help women recover faster from urinary retention (difficulty emptying your bladder) after pelvic reconstructive surgery. You might be able to join if you are 18 or older, can speak and read English, and have urinary retention after your surgery. The study compares Tamsulosin to a placebo (an inactive pill that looks the same) to see if Tamsulosin shortens how long you experience urinary retention. Researchers also want to see if it leads to fewer urinary tract infections and a better quality of life. The study is currently unclear on its recruitment status, but plans to enroll 154 women.

Study design
This is a double-blind, randomized, placebo-controlled study, meaning neither you nor your doctor will know if you're receiving Tamsulosin or the placebo. It plans to include 154 women.
What's involved
If you join, you will take 10 capsules daily of either Tamsulosin or a placebo until your urinary retention resolves or for up to 10 days.
Compensation
Not stated in the trial record.
Follow-up
The study will track how long your urinary retention lasts, up to a 10-day course.

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NCT04597372

Impact of Tamsulosin on Post-Operative Urinary Retention Following Pelvic Reconstructive Surgery

Recruiting
PHASE2Ages 18+InterventionalTreatment
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
~154 participants
Updated 2026-03-20 on ClinicalTrials.gov
What's tested:TamsulosinPlacebo

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To determine the impact of Tamsulosin on duration of urinary retention
Measured over Date of failed retrograde voiding trial until resolution of post-operative urinary retention or a 10-day course
Urinary Retention Postoperative
1 sites across 1 states
Pennsylvania1
  • Lindsay Turner, MD · PRINCIPAL_INVESTIGATOR · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

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Eligibility criteria

Inclusion

18 years or older
willing and able to provide informed consent
postoperative urinary retention as defined by a failed RGVT prior to hospital discharge
Ability to speak and read English
Tolerate pill ingestion

Exclusion

allergy/intolerance to Tamsulosin or sulfa drugs
preoperative history of urinary retention as defined by preoperative post void residual of \>150mL
current use of alpha antagonist medication for hypertension
severe dementia
end stage renal or liver disease
history of severe heart failure or major cardiovascular event in the last 6 months
  • To determine the impact of Tamsulosin on duration of urinary retentionDate of failed retrograde voiding trial until resolution of post-operative urinary retention or a 10-day course

    The primary outcome is duration of postoperative urinary retention measured in days following failed retrograde voiding trial.