Observational Study on Heart Disease in Women

This observational study, called WOMEN FiRST, is looking at how different strategies for treating coronary artery disease (blockages in the heart's arteries) affect women. Researchers are collecting information from 500 women who have suspected heart problems and are undergoing standard heart procedures like cardiac catheterization (a test that looks at your heart's blood vessels). The study will compare how well treatments based on FFR (Fractional Flow Reserve) and iFR (instantaneous wave-free ratio) measurements work. Success will be measured by looking at how many women need repeat procedures, have a non-fatal heart attack, or a non-fatal stroke over 5 years. The study is currently unclear on its recruitment status.

Study design
This is an observational study involving 500 women. It collects information from participants without assigning specific interventions.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 5 years to track repeat revascularization, non-fatal myocardial infarction, and non-fatal stroke.

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NCT04599192

Fractional Flow Reserve and Instantaneous Free-wave Ratio Revascularization Strategies in Women

Enrolling by Invitation
Not specifiedAges 18+Observational
Yale University
~500 participants
Updated 2025-11-05 on ClinicalTrials.gov
What's tested:No study intervention

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Repeat revascularization
Measured over 5 years
+3 more outcomes measured
Coronary Disease
Percutaneous Coronary Intervention
Exercise Test
Myocardial Perfusion Imaging
Cardiac Catheterization
1 sites across 1 states
Connecticut1
  • Elissa Altin, MD · PRINCIPAL_INVESTIGATOR · Yale University

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Repeat revascularization5 years

    Repeat revascularizations will be documented throughout the course of the 5 year follow up period

  • Non-fatal myocardial infarction5 years

    Non-fatal myocardial infarctions will be documented throughout the course of the 5 year follow up period

  • Non-fatal stroke5 years

    Non-fatal strokes will be documented throughout the course of the 5 year follow up period

  • Cardiovascular death5 years

    Cardiovascular related death will be documented throughout the course of the 5 year follow up period